The brain and spinal cord together form the nervous control centre of our body. This is where impulses originate that are transmitted to all muscles and other organs via the nervous system. Disorders of the brain-nerve-muscle axis are common, difficult to diagnose, disabling, often undertreated and accordingly, a severe burden for the individual and society.

Within the Medical Research Profile 'Translational Neuroscience', innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles. Clinicians and researchers work closely together on key clinical questions to unravel the molecular basis and identify novel intervention targets of the disease.