This course will give a broad overview of topics in meta-analysis. Most standard topics in meta-analysis will be covered, such as risk of bias analysis, searching studies, fixed versus random effect models, heterogeneity, publication bias, differences between meta-analysis of randomized trials and meta-analysis observational studies. In practical sessions (STATA, no pre-knowledge required) students will perform a standard meta-analysis by themselves. The course will briefly cover some more advanced topics (bivariate meta-analysis, combining different metrics, network analysis).
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PROGRAM |
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Wednesday 10 April 2019 Lecture hall 2 |
08.30 |
Registration |
09:00 |
Introduction to the course
Dr. Olaf Dekkers |
09:10 |
Meta-analysis: Why &how?
Dr. Olaf Dekkers |
10:15 |
Break |
10:30 |
The statistical approach
Dr. Marta Fiocco |
11:30 |
Heterogeneity and Risk of bias
Dr. Olaf Dekkers |
12:30 |
Break and lunch |
13:00 |
Searching for literature: potentials and pitfalls
Karin van der Hoorn (Geb-1 J1-82) |
15:15 |
Pooling effect estimates I
Prof. dr. Saskia le Cessie |
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Thursday 11 April 2019 Lecture hall 3 |
08:45 |
Registration |
09:00 |
Publication bias
Dr. Olaf Dekkers |
09:30 |
Heterogeneity: statistical
Dr. Marta Fiocco |
10:30 |
Break |
10:45 |
Publication bias: statistical
Dr. Marta Fiocco |
12:00 |
Break and lunch |
12:45 |
Practical session: risk of bias analysis
Dr. Olaf Dekkers |
13:45 |
Meta-analysis of observational studies
Dr. Olaf Dekkers |
14:45 |
Break |
15:00 |
Pooling different effect measures
Dr. Olaf Dekkers |
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Friday 12 April 2018 Lecture hall 2 |
08:45 |
Registration |
09:00 |
Pooling effect estimates II
Prof. dr. Saskia le Cessie |
10:00 |
Break |
10:15 |
Practical in STATA I
Prof. dr. Saskia le Cessie |
12:00 |
Break and lunch |
12:30 |
Practical in STATA II
Prof. dr. Saskia le Cessie en Katarina Papadimitropoulou |
13:45 |
Tips and tricks for data-extraction
Prof. dr. Saskia le Cessie |
14:30 |
Break |
14:45 |
Meta-analysis of diagnostical studies
Prof. dr. Saskia le Cessie |
15:45 |
Final remarks |
Prof. dr. Cessie, S. Le (EPI)
LUMC, Hoogleraar Epidemiologie
Prof. Dr. O.M. Dekkers
Endocrinoloog en klinisch epidemioloog, LUMC
LUMC
Albinusdreef 2, 2333 ZA Leiden
Building: Gebouw 1
Route: 766
Room: CZ-2
Participation fee: € 550,-
Participation fee LUMC employees/PhD students: € 150,-
The course is free of charge for students of the Leiden University. Make sure that you mention your student number.